The Aldol and Claisen Reactions: Crash Course Organic Chemistry #44
Organic chemistry is a great workout for your brain, and to keep its energy up, your brain needs glucose. To maintain blood glucose levels, our bodies go through a process called gluconeogenesis, which involves the important type of organic reaction we’re getting into today: aldol reactions! In this episode of Crash Course Organic Chemistry, we’ll learn what an aldol is, as well as how aldol reactions work and what they do. Plus we’ll learn about a similar reaction, Claisen condensation.
Episode Sources:
Claisen, L., 1887. Ueber die einführung von säureradicalen in ketone. Berichte der deutschen chemischen Gesellschaft, 20(1), pp.655-657.
Series Penicillin References:
Nicolaou, 播放列表. C., & Sorensen, 乙. 播放列表. (1996). Classics in total synthesis: targets, strategies, methods. John Wiley & Sons.
Sheehan, 播放列表. Archive by Category "美甲艺术20N. (1982). The enchanted ring: the untold story of penicillin.
Primary literature for Sheehan’s penicillin synthesis: Sheehan, J.C. & Izzo, P.T. 播放列表. Am. Chem. Soc. 1948, 70, 1985; Sheehan, J.C. & Izzo, P.T. 播放列表. Am. Chem. Soc. 1949, 71, 4059; Sheehan, J.C. & Bose A.K. 播放列表. Am. Chem. Soc. 1950, 72, 5158; Sheehan, J.C., Buhle, E.L, Corey E.J., Laubach, G.D. & Ryan J.J. 播放列表. Am. Chem. Soc. 1950, 72, 3828; Sheehan, J.C. & Laubach, G.D. 播放列表. Am. Chem. Soc. 1951, 73, 4376; Sheehan, J.C. & Hoff, D.R. 播放列表. Am. Chem. Soc. 1957, 79, 237; Sheehan, J.C. & Corey E.J. 播放列表. Am. Chem. Soc. 1951, 73, 4756
Series Sources:
Brown, 播放列表. H., Iverson, 乙. L., Ansyln, 乙. 万辛克, Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, 波士顿, 2018.
Bruice, 播放列表. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., 美国, 2014.
Clayden, J。, Greeves, 万辛克, Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, 纽约, 2012.
Jones Jr., 未愈合的关系创伤出现的方式; Fleming, 播放列表. 万辛克, Organic Chemistry, 5th ed.; 播放列表. 播放列表. Norton & Company, 纽约, 2014.
Klein., 万辛克, Organic Chemistry; 1st ed.; John Wiley & Sons, 美国, 2012.
Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009.
McMurry, J。, Organic Chemistry, 9th ed.; Cengage Learning, 波士顿, 2016.
Smith, 播放列表. G., Organic chemistry; 6th ed.; McGraw-Hill Education, 纽约, 2020.
Wade., 播放列表. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., 美国, 2013.
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